Born in Berlin, Nancy Weißbach graduated from The Liszt School of Music Weimar and from the Royal Conservatoire at The Hague with Christina Deutekom and Diane Forlano. She later participated in the Britten-Pears School for Advanced Musical Studies (Galina Wischnewskaja) and at the Scuola Civica in Milan (Rodolfo Celletti), after which she sang the lead role in Henry Purcell's "Dido and Aeneas" at the Festival of Ambronay.

From 1999 to 2001, under contract as principal soloist, at  Südthüringischen Staatstheater at Meiningen , Nancy Weißbach played the roles of The Marschallin ("Der Rosenkavalier / The Knight of the Rose" Richard Strauss) and Santuzza ("Cavalleria Rusticana" Pietro Mascagni) in new productions, both of which she reprised in 2001/2002. She was also invited to interpret the foreign Princess ("Rusalka" Antonín Dvořák) in 2002, 2003 and 2004 at the  Staatstheater Schwerin .

In 2002 she sang Chrysothemis for  Opéra National du Rhin, Strasbourg  in a new production of "Elektra" (Richard Strauss) directed by Stéphane Braunschweig, a role which she recreated in the same year at  L'Opéra National de la Monnaie, Brussels  and then in 2003 in  Mannheim .

In Mai and June 2003 she sang Gutrune and third Norn ("Götter­dämmerung / Twilight of the Gods" Richard Wagner) at the  Théâtre du Capitole in Toulouse , directed by Pinchas Steinberg and staged by Nicolas Joel.

She performed under the baton of Daniel Inbal Beethoven's 9th and Mahler's 2nd Symphony as well as the title role in "Euryanthe" (Carl Maria von Weber) at the  Opéra National du Rhin, Strasbourg  in 2004.

In the same year she sang Ariadne ("Ariadne auf Naxos / Ariadne on Naxos" Richard Strauss) at the  Theatro Lirico "Guiseppe Verdi" in Trieste  followed by Agathe ("Der Freischütz" Carl Maria von Weber) at the  Opéra Royal de Wallonie, Liège  in March 2005.

During season 2005/2006 she sang Vitellia ("La Clemenza di Tito" Wolfgang Amadeus Mozart) directed by Uwe Eric Laufenberg at the  Music Festival Potsdam Sanssouci , The Marschallin under Maximillian Schell and conducted by Asher Fisch at  New Israeli Opera Tel Aviv , and Ariadne in  Limoges  and at the  Stadttheater Bozen / Bolzano .

In 2007 she performed Richard Strauss' "Vier letzte Lieder" and the title role The Governess ("The Turn of the Screw" Benjamin Britten) in  Liège  and at the  Opera de Tenerife  too, afterwards  Ariadne  at the  Opera in Metz .

In 2008 she returned to  Opéra National du Rhin  for Chrysothemis ("Elektra" Richard Strauss). At the  Staatstheater Nuremberg  she sang The Marschallin.
Numerous concerts took her to Italy and Belgium with, among others, Richard Wagner's "Wesendonck Lieder" and Ludwig van Beethoven's ninth Symphony.

During season 2009/2010 she sang the "Wesendonck Lieder" (Richard Wagner) under Jun Märkl at the  Cologne Philharmonic Hall  and The Marschallin ("Der Rosenkavalier" Richard Strauss) at the  Cologne Opera  staged by Günter Krämer and conducted by Patrik Ringborg.
At the  Theatro Lirico "Guiseppe Verdi" in Trieste  she sang Elisabeth ("Tannhäuser" Richard Wagner).

In February/March 2011 she will sing Gutrune and third Norn ("Götter­dämmerung / Twilight of the Gods" Richard Wagner) under Marko Letonja and staged by David McVicar at the  Opéra National du Rhin in Strasbourg  and in July Elisabeth (Tannhäuser) at the  Tyrolean Festival Erl  under Gustav Kuhn.

Nancy Weißbach, who speaks English, French, Italian, Dutch and Russian in addition to her native language, lives in Berlin and in Southern France.